Biodiversity – the essential variety of life forms on Earth – continues to decline in every region of the world, significantly reducing nature’s capacity to contribute to people’s wellbeing. This alarming trend endangers economies, livelihoods, food security and the quality of life of people everywhere, according to four landmark regional science reports released at the 6th Plenary of the Intergovernmental science-policy Platform on Biodiversity and Ecosystem Services (IPBES) in Medellin, Colombia in March.